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What Tests Are Needed In The Diagnosis Of Purpura Nephritis

Time:  2014-01-10 13:54

What Tests Are Needed In The Diagnosis Of Purpura NephritisPurpura nephritis is caused by Henoch-Schonlein purpura, which is an autoimmune disease. Because the symptoms and pathologic changes of purpura nephritis are similar with the symptoms caused by many other kidney diseases, many medical tests will be needed in diagnosing this disease.

1.Blood routine examination: this is an important aspect in checking patient’s condition, and patient’s bleeding time, blood clotting time, etc, are the reflections of patient’s real condition.

2.Immunological examination: if patient has lupus, there will be some changes in his immune system. By taking immunological examination, the IgA level may be found to have rise, and patient will also have abnormal level of IL-6 and TNF-a.

3.Kidney function test: in the kidney function test, when patient has purpura nephritis, he may be found to have increased level of urea nitrogen and creatinine, but patient’s glomerular filtration rate will decrease.

4.Urine test: in patient’s urine test, because purpura nephritis can damage patient’s small blood vessels, which may cause patient to have red urine, proteinuria and cylindruria, etc.

5.Renal biopsy: renal biopsy is an effective way to check patient’s kidney condition. In this test, cell proliferation will be found in glomerular mesangial cells.

While renal biopsy is also divided into immunofluorescence examination, electron microscopy examination, and light microscope examination.

Besides, as we have said, the symptoms and pathologic changes of purpura nephritis are very like with some kidney diseases, so purpura nephritis should be identified with some kidney diseases. The diseases that can cause similar pathologic changes are acute nephritis, lupus nephritis, primary small vessel vasculitis, IgA nephropathy.

In the end, if you have any other doubt in dealing with purpura nephritis, you can contact our online experts, and we are glad to help you.

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