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What Causes Polycystic Kidney Disease (PKD)

Time:  2014-01-10 10:40

What Causes Polycystic Kidney Disease (PKD)Characterized by clusters of kidney cysts, Polycystic Kidney Disease (PKD) is a genetic disorder. According to different causes, PKD is divided into two types, ADPKD and ARPKD. Knowing their causes can guide patients to learn the severity of PKD and choose correct treatment option.

Firstly, learn more about Polycystic Kidney Disease

Most often, PKD isn’t limited in kidneys, although kidneys are usually the first affected organs. As time goes on, cysts may spread to patients’ liver, pancreas and brain. With the growth of kidney cysts, a series of complications will appear, including, high blood pressure, back pain, hematuria, urinary tract infections, etc. It is reported that about 50% of PKD patients have kidney failure at age 60. From this point, knowing the causes of this kidney disease is very necessary.

Causes of Polycystic Kidney Disease

Abnormal genes are the reasons for PKD, and two conditions can lead to this type of kidney disease. In some cases, genetic defects causing PKD runs in families, so many PKD patients find there are other patients in their family members. In some others cases, patients say there isn’t other people having this disease.

- ADPKD: It refers to autosomal dominant polycystic kidney disease. If one parent has ADPKD, each child has a 50% chance of getting ADPKD. Its signs and symptoms usually don’t occur until age 30 or 40.

- ARPKD: It refers to autosomal recessive polycystic kidney disease (ARPKD). ARPKD is one childhood kidney disorder, and patients usually die before 20 years old. Therefore, it is more serious than ADPKD.

For people with Polycystic Kidney Disease, making clear the causes of their disease can help them find out how to manage their illness condition. If anything unclear, you can consult our doctor online.

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