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Why Patient With Kidney Disease Can Have Nephrotic Syndrome

Time:  2014-01-10 10:39

Why Patient With Kidney Disease Can Have Nephrotic SyndromePatients with kidney disease may have nephrotic syndrome, which is a severe damage condition for them. While why patient with kidney disease can have nephrotic syndrome?

What is nephrotic syndrome?

Nephrotic syndrome is a condition that the permeability of patient’s filtration membrane increases and patient’s GFR decreases at the same time. Patients with nephrotic syndrome will have its obvious symptoms, and that is called “three high and one low”, which refers to massive proteinuria, severe edema, hyperlipidemia, and hypoproteinemia.

Nephrotic syndrome can be caused by many kidney diseases, such as FSGS, IgA nephropathy, lupus nephritis, minimal change disease, etc.

Why patient with kidney disease can have nephrotic syndrome?

As we have said, many kidney diseases can cause patient to have nephrotic syndrome, and these diseases have their common point.

Kidney disease is due to the accumulation of foreign material in kidney, and as the flow of patient’s blood, foreign material can accumulate in many parts of patient’s kidney, like kidney tubule, glomeruli, etc.

And some kidney diseases, like FSGS and lupus nephritis, can cause damage in the filtration membrane of patient’s glomeruli. While filtration membrane has the function of filtering the wastes in patient’s blood, and it keeps the useful substances in patient’s blood. So when patient’s filtration membrane is damaged, its permeability may be increased, and that will lead to lots of nutrients leaking out from patient’s blood.

That is the main reason why patient with kidney disease can have nephrotic syndrome. Because proteinuria can cause many severe effects, proteinuria can cause patient to have severe edema and hypoproteinemia, and that is a major reason of patient’s special symptoms.

These are the basic points about nephrotic syndrome. In the end, if you have any other trouble in dealing with nephrotic syndrome, you can contact our online experts, and we are glad to help you.

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