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What Causes FSGS

Time:  2014-01-07 15:30

What Causes FSGSWe need to find out the causes of FSGS and only in this way, can we take the right measures and choose the right treatment. Well, what are the causes of FSGS?

FSGS (Focal Segmental Glomerulosclerosis) is an illness that mainly involves in glomeruli; and according to clinical studies, usually no more than 50% of glomeruli are damaged. Glomerulus is a network of capillaries that performs the first step of filtering blood. During this process, wastes in the blood can be filtered out with excess fluid as the form of urine. However, when glomeruli are injured and fail to function properly, some nutrients like protein will leak out at the same time. This is the reason why FSGS patients are always detected with excess protein in urine.

Nephrotic Syndrome is a kidney problem marked by massive protein in urine, swelling, hyperlipemia and hypoproteinemia and it is said FSGS is the leading cause of this problem, especially among young people. Therefore, for patients who are diagnosed with FSGS, they need to be alert about Nephrotic Syndrome.

FSGS can be primary and secondary. For primary FSGS, the cause is unknown. However, for secondary FSGS, in our daily life, there are many conditions that can cause it like improper usage of some medicines, taking drugs, disorder of humoral immunity and abnormal hemodynamics and so on. With different causes, different treatment methods are needed. Effective treatment helps to stop illness progression and prevent kidney failure. However, if FSGS is treated in the wrong say, kidney condition keeps worsening and this may push patients into dialysis or kidney transplant earlier. Therefore, choosing the right treatment method is very important.

FSGS is not deadly in early, but if left alone, it will develop to end stage kidney failure and thus cause a series of fatal complications like heart failure. Therefore, once being diagnosed with FSGS, we need to have further tests to find out its causes as quickly as possible, so as to stop illness from deteriorating.

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